Biography:

In spring 2015, I will join the School of Biosciences at the University of Kent as an independent Leverhulme Research Fellow. I am currently based at the Max-Planck Institute of Biochemistry where I am employed as a Researcher in the group of Stephan Gruber. Here I have initiated kinetic studies on in vitro reconstituted Bacillus subtilis Structural-Maintenance-of-Chromosome complex.

My research career began in bioinformatics at the Edward Jenner Institute. In 2006 I moved to the MRC National Institute for Medical Research (NIMR) for a PhD. I performed transient kinetic measurements to investigate the activity of bacterial DNA helicases, PcrA and RecG. As a Post-Doctoral Research Associate at NIMR I was able to learn and perform single molecule measurements on the PcrA helicase using this assay. This work established that a monomeric helicase is capable on unwinding plasmid lengths of DNA, a controversial point in the field for many years.

In 2009 I was awarded an EMBO Fellowship to move to the LMU Munich. My main focus was to understand the role regulatory proteins play on myosin VI. This work consisted of solution kinetics, gel filtration and single molecule measurements. I was able to show how binding partners regulate dimerization of the motor from an auto-inhibited state. 

Aside from my research I have been able to supervise undergraduate, masters and PhD students. I am also an organiser and tutor of the biennial EMBO kinetics course held in Canterbury.

 

 

Oct 2015:             MRC Career Development Fellow

Schools of Biosciences - University of Kent

Canterbury, UK

 

April 2015:          Leverhulme Early Career Research Fellow

Schools of Biosciences - University of Kent

Canterbury, UK

 

 

2013 - 2015        Senior Post-Doc Researcher with Stephan Gruber

Max-Planck Institute for Biochemistry, Munich, Germany

 

2010 - 2013        EMBO Long Term Fellow with Claudia Veigel

LMU Munich, Munich, Germany

 

2009 - 2010        Post-Doctoral Research Associate with Martin Webb

MRC National Institute for Medical Research, London, UK

 

2006 - 2009        PhD with Martin Webb

MRC National Institute for Medical Research, London, UK

 

2002 - 2006        BSc Biochemistry (1st Class Hons)

                                               University of Wales - Aberystwyth

 

Awards

 

2015: MRC Career Development Award

2014: Leverhulme Early Career Fellowship

2009: EMBO Long Term Fellowship